Weight Loss Resistance: Here’s How Hormones Impact Weight Loss

You’re doing everything correctly: you count calories, reduce your sugar intake, cut out most processed foods, and hit the gym four times every week. Yet despite your most focused effort, those last 10 pounds refuse to vacate. 

Weight loss resistance differs from plateauing. Almost everyone hits a roadblock at some point on their weight-loss journey, but eventually, they overcome that plateau and continue losing weight. But when you stay consistently on course and yet weeks — even months — go by without the scales budging, that’s weight loss resistance.

“Your body is a chemistry lab, not a bank account, and the calories-in-calories-out model is woefully outdated because it fails to account for the numerous variables that can affect fat loss,” says JJ Virgin, CNS, who describes weight loss resistance as not losing one to three pounds of fat every week when you’re following a strict protocol. 

Many things contribute to weight loss resistance, including pharmaceutical and over-the-counter medications, food allergies or sensitivities, thyroid or adrenal imbalances, and genetics.

From basic to advanced, MaxLiving offers three tiers of weight loss bundles to help you reach your health goals.

This bundle includes:

Metabolix Burn
Pro L-Carnitine Formula

This bundle includes:

Metabolix Burn

Pro L-Carnitine Formula

Grass-Fed Whey Protein (Chocolate or Vanilla)

This bundle includes:

Metabolix Burn

Pro L-Carnitine Formula

Grass-Fed Whey Protein (Chocolate or Vanilla)

MaxLiving Essentials Bars (Box of 12)

Learn more about each product in the Weight Loss Bundles!

Weight Loss Perspective

The latest statistics show that more than 2 in 3 American adults are overweight or obese.(1) Obesity-related conditions include heart disease, stroke, type 2 diabetes, and certain cancers, many of which are preventable.(2) Even modest weight loss, such as 5 to 10 percent of your total body weight, can improve your self-esteem as well as various health factors including blood pressure, blood cholesterol, and blood sugar.(3) 

Incorporating these strategies can help boost weight loss and improve body composition to better overall health. 

†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


1. Overweight & Obesity Statistics. niddk.nih.gov. https://www.niddk.nih.gov/health-information/health-statistics/overweight-obesity. Published August 2017. Accessed November 8, 2019. 

2. Adult Obesity Facts. cdc.gov. https://www.cdc.gov/obesity/data/adult.html. Reviewed August 13, 2018. Accessed November 8, 2019. 

3. Losing Weight. cdc.gov. https://www.cdc.gov/healthyweight/losing_weight/index.html. Reviewed February 13, 2018. Accessed November 8, 2019. 

4. Ogura T, Tashiro M, Masud M, Watanuki S, Shibuya K, Yamaguchi K, Itoh M, Fukuda H, Yanai K, et al. Cerebral metabolic changes in men after chiropractic spinal manipulation for neck pain. Altern Ther Health Med. 2011;17(6):12-7. https://www.ncbi.nlm.nih.gov/pubmed/22314714?report=abstract. Published November 2011. Accessed November 8, 2019. 

5. Vander Wal JS, Gupta A, Khosla P, Dhurandhar NV, et al. Egg breakfast enhances weight loss. Int J Obes (Lond). 2008;32(10):1545-1551. doi: 10.1038/ijo.2008.130. 

6. Roberts SB. Glycemic index and satiety. Nutr Clin Care. 20013;6(1):20-26. Published January 2003. Accessed November 8, 2019. 

7. Anderson GH, Woodend D, et al. Effect of Glycemic Carbohydrates on Short-term Satiety and Food Intake. Nutrition Reviews. 2003;61(5):S17-S26. doi: 10.1301/nr.2003.may.S17-S26. 

8. Pepino MY, Tiemann CD, Patterson BW, Wice BM, Klein S, et al. Sucralose Affects Glycemic and Hormonal Responses to an Oral Glucose Load. Diabetes Care. 2013;36(9):2530-2535. doi: 10.2337/dc12-2221. 

9. Fowler SP, Williams K, Resendez RG, Hunt KJ, Hazuda HP, Stern MP, et al. Fueling the Obesity Epidemic? Artificially Sweetened Beverage Use and Long-term Weight Gain. Obesity. 2008;16(8):1894-1900. doi: 10.1038/oby.2008.284. 

10. Ludy MJ, Mattes RD, et al. The effects of hedonically acceptable red pepper doses on thermogenesis and appetite. Physiol Behav. 2011;102(3-4):251-258. doi: 10.1016/j.physbeh.2010.11.018. 

11. Dennis EA, Dengo AL, Comber DL, Flack KD, Salva J, Davy KP, Davy BM, et al. Water Consumption Increases Weight Loss During a Hypocaloric Diet Intervention in Middle-aged and Older adults. Obesity (Silver Spring). 2010;18(2):300-307. doi: 10.1038/oby.2009.235. 

12. Malik VS, Schulze MBB, Hu FB, et al. Intake of sugar-sweetened beverages and weight gain: a systematic review. Am J Clin Nutr. 2006;84(2):274-288. doi: 10.1093/ajcn/84.1.274. 

13. Roberts C, Troop N, Connan F, Treasure J, Campbell IC, et al. The effects of stress on body weight: biological and psychological predictors of change in BMI. Obesity (Silver Spring). 2007;15(12):3045-3055. doi: 10.1038/oby.2007.363. 

14. How Much Sleep Do We Really Need? sleepfoundation.org. https://www.sleepfoundation.org/articles/how-much-sleep-do-we-really-need. Accessed November 8, 2019. 

15. Beccuti G, Pannain S, et al. Sleep and obesity. Curr Opin Clin Nutr Metab Care. 2011;14(4):402-412. doi: 10.1097/MCO.0b013e3283479109. 

16. Sharma S, Kavuru M, et al. Sleep and Metabolism: An Overview. Int J Endocrinol. 2010;2010:270832. doi: 10.1155/2010/270832. 

17. Boutcher SH. High-Intensity Intermittent Exercise and Fat Loss. J Obes. 2011;2011:868305. doi: 10.1155/2011/868305. 

18. Booth FW, Roberts CK, Laye MJ, et al. Lack of exercise is a major cause of chronic diseases. Compr Physiol. 2012;2(2). 1143-1211. doi: 10.1002/cphy.c110025. 

19. Lee BA, Oh DJ, et al. Effect of regular swimming exercise on the physical composition, strength, and blood lipid of middle-aged women. J Exerc Rehabil. 2013;11(5).266-271. doi: 10.12965/jer.150242.

20. Ohkawara K, Tanaka S, Miyachi M, Ishikawa-Takata K, Tabata I, et al. A dose-response relation between aerobic exercise and visceral fat reduction: systematic review of clinical trials. Int J Obes (Lond). 2007;31(12):1786-1797. https://www.ncbi.nlm.nih.gov/pubmed/17637702. Published July 17, 2007. Accessed November 8, 2019. 

21. Blond MB, Rosenkilde M, Gram AS, Tindborg M, Christensen AN, Quist JS, Stallknecht BM, et al. How does 6 months of active bike commuting or leisure-time exercise affect insulin sensitivity, cardiorespiratory fitness and intra-abdominal fat? A randomized controlled trial in individuals with overweight and obesity. Br J Sports Med.2019;53:1183-1192. https://bjsm.bmj.com/content/53/18/1183.info. Published March 16, 2019. Accessed November 8, 2019. 

22. Boutcher SH. High-Intensity Intermittent Exercise and Fat Loss. J Obes. 2011;2011:868305. doi: 10.1155/2011/868305. 

23. Latini G, Gallo F, Iughetti L, et al. Toxic environment and obesity pandemia: Is there a relationship? Ital J Pediatr. 2010;36:8. doi: 10.1186/1824-7288-36-8. 

24. Kelishadi R, Poursafa P, Jamshidi F, et al. Role of Environmental Chemicals in Obesity: A Systematic Review on the Current Evidence. J Environ Public Health. 2013;2013:896789. doi: 10.1155/2013/896789. 


This content is for information purposes only. Any statement or recommendation in this publication does not take the place of medical advice nor is meant to replace the guidance of your licensed healthcare practitioner. These statements have not been evaluated by the Food and Drug Administration. MaxLiving information is and products are not intended to diagnose, cure, treat, or prevent any disease or provide medical advice. Decisions to use supplements to support your specific needs should be considered in partnership with your licensed healthcare practitioner.